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Growth Disorders

MedGen UID:
5389
Concept ID:
C0018273
Pathologic Function
Synonyms: Disorder, Growth; Growth Disorder; Growth, Stunted; Stunted Growth; Stunting; Stuntings

Definition

Deviations from the average values for a specific age and sex in any or all of the following: height, weight, skeletal proportions, osseous development, or maturation of features. Included here are both acceleration and retardation of growth. [from MeSH]

Professional guidelines

PubMed

Mauras N, Ross J, Mericq V
Endocr Rev 2023 Jan 12;44(1):1-13. doi: 10.1210/endrev/bnac014. PMID: 35639981
Zhou E, Hauser BR, Jee YH
Curr Opin Pediatr 2021 Aug 1;33(4):458-463. doi: 10.1097/MOP.0000000000001033. PMID: 34101704Free PMC Article
Wolff H, Fischer TW, Blume-Peytavi U
Dtsch Arztebl Int 2016 May 27;113(21):377-86. doi: 10.3238/arztebl.2016.0377. PMID: 27504707Free PMC Article

Recent clinical studies

Etiology

Woelfle J, Schnabel D, Binder G
Dtsch Arztebl Int 2024 Feb 9;121(3):96-106. doi: 10.3238/arztebl.m2023.0247. PMID: 38051162Free PMC Article
Linglart A, Merzoug V, Lambert AS, Adamsbaum C
Ann Endocrinol (Paris) 2017 Jun;78(2):114-122. Epub 2017 May 8 doi: 10.1016/j.ando.2017.04.011. PMID: 28495326
Fuente R, Gil-Peña H, Claramunt-Taberner D, Hernández O, Fernández-Iglesias A, Alonso-Durán L, Rodríguez-Rubio E, Santos F
Rev Endocr Metab Disord 2017 Mar;18(1):107-115. doi: 10.1007/s11154-017-9408-1. PMID: 28130634
de Onis M, Branca F
Matern Child Nutr 2016 May;12 Suppl 1(Suppl 1):12-26. doi: 10.1111/mcn.12231. PMID: 27187907Free PMC Article
Zimmermann MB
Endocr Rev 2009 Jun;30(4):376-408. Epub 2009 May 21 doi: 10.1210/er.2009-0011. PMID: 19460960

Diagnosis

Chiarelli F
Minerva Pediatr 2020 Dec;72(6):449-451. Epub 2020 Jul 29 doi: 10.23736/S0026-4946.20.06018-1. PMID: 32731737
Valdes A, Cervantes J, Delgado Y, Valdes M, Granados H
Pediatr Ann 2018 Jan 1;47(1):e29-e35. doi: 10.3928/19382359-20171215-02. PMID: 29323694
Taylor-Miller T, Simm PJ
Aust Fam Physician 2017 Dec;46(12):913-917. PMID: 29464228
Braun LR, Marino R
Pediatr Rev 2017 Jul;38(7):293-304. doi: 10.1542/pir.2016-0178. PMID: 28667232
Kiess W, Penke M, Pfäffle R, Körner A, Kratzsch J
J Pediatr Endocrinol Metab 2015 Sep;28(9-10):971-3. doi: 10.1515/jpem-2015-0321. PMID: 26353173

Therapy

Miller BS, Blair JC, Rasmussen MH, Maniatis A, Mori J, Böttcher V, Kim HS, Bang RB, Polak M, Horikawa R
J Clin Endocrinol Metab 2023 Nov 17;108(12):3090-3099. doi: 10.1210/clinem/dgad394. PMID: 37406251Free PMC Article
Antoniazzi F, Cavarzere P, Gaudino R
Minerva Endocrinol 2015 Jun;40(2):129-43. PMID: 25734895
Bhutta ZA, Das JK, Rizvi A, Gaffey MF, Walker N, Horton S, Webb P, Lartey A, Black RE; Lancet Nutrition Interventions Review Group, the Maternal and Child Nutrition Study Group
Lancet 2013 Aug 3;382(9890):452-477. Epub 2013 Jun 6 doi: 10.1016/S0140-6736(13)60996-4. PMID: 23746776
Joshi N, Rajeshwari K
J Postgrad Med 2009 Oct-Dec;55(4):296-300. doi: 10.4103/0022-3859.58942. PMID: 20083885
Keating GM
BioDrugs 2008;22(3):177-88. doi: 10.2165/00063030-200822030-00004. PMID: 18481900

Prognosis

Mameli C, Guadagni L, Orso M, Calcaterra V, Wasniewska MG, Aversa T, Granato S, Bruschini P, d'Angela D, Spandonaro F, Polistena B, Zuccotti G
Endocrine 2024 Jul;85(1):91-98. Epub 2024 Mar 18 doi: 10.1007/s12020-024-03778-4. PMID: 38498128Free PMC Article
Hawkes G, Yengo L, Vedantam S, Marouli E, Beaumont RN; GIANT Consortium, Tyrrell J, Weedon MN, Hirschhorn J, Frayling TM, Wood AR
PLoS Genet 2023 Sep;19(9):e1010934. Epub 2023 Sep 21 doi: 10.1371/journal.pgen.1010934. PMID: 37733769Free PMC Article
Taylor-Miller T, Simm PJ
Aust Fam Physician 2017 Dec;46(12):913-917. PMID: 29464228
Clermont A, Walker N
J Nutr 2017 Nov;147(11):2132S-2140S. Epub 2017 Sep 13 doi: 10.3945/jn.116.243766. PMID: 28904118
Kozin SH, Zlotolow DA
J Hand Surg Am 2015 Oct;40(10):2090-8. Epub 2015 Sep 1 doi: 10.1016/j.jhsa.2015.03.033. PMID: 26341718

Clinical prediction guides

Mertens A, Benjamin-Chung J, Colford JM Jr, Hubbard AE, van der Laan MJ, Coyle J, Sofrygin O, Cai W, Jilek W, Rosete S, Nguyen A, Pokpongkiat NN, Djajadi S, Seth A, Jung E, Chung EO, Malenica I, Hejazi N, Li H, Hafen R, Subramoney V, Häggström J, Norman T, Christian P, Brown KH, Arnold BF; Ki Child Growth Consortium
Nature 2023 Sep;621(7979):558-567. Epub 2023 Sep 13 doi: 10.1038/s41586-023-06480-z. PMID: 37704720Free PMC Article
Vaivada T, Akseer N, Akseer S, Somaskandan A, Stefopulos M, Bhutta ZA
Am J Clin Nutr 2020 Sep 14;112(Suppl 2):777S-791S. doi: 10.1093/ajcn/nqaa159. PMID: 32860401Free PMC Article
Kalafat E, Khalil A
Curr Opin Obstet Gynecol 2018 Dec;30(6):344-354. doi: 10.1097/GCO.0000000000000490. PMID: 30299319
Giuliani F, Cheikh Ismail L, Bertino E, Bhutta ZA, Ohuma EO, Rovelli I, Conde-Agudelo A, Villar J, Kennedy SH
Am J Clin Nutr 2016 Feb;103(2):635S-47S. Epub 2016 Jan 20 doi: 10.3945/ajcn.114.106310. PMID: 26791186Free PMC Article
Prentice AM, Darboe MK
Nestle Nutr Workshop Ser Pediatr Program 2008;61:197-210. doi: 10.1159/000113495. PMID: 18196953

Recent systematic reviews

Gusnedi G, Nindrea RD, Purnakarya I, Umar HB, Andrafikar, Syafrawati, Asrawati, Susilowati A, Novianti, Masrul, Lipoeto NI
Asia Pac J Clin Nutr 2023;32(2):184-195. doi: 10.6133/apjcn.202306_32(2).0001. PMID: 37382316
Katoch OR
Nutrition 2022 Apr;96:111565. Epub 2021 Dec 11 doi: 10.1016/j.nut.2021.111565. PMID: 35066367
Thurstans S, Sessions N, Dolan C, Sadler K, Cichon B, Isanaka S, Roberfroid D, Stobaugh H, Webb P, Khara T
Matern Child Nutr 2022 Jan;18(1):e13246. Epub 2021 Sep 5 doi: 10.1111/mcn.13246. PMID: 34486229Free PMC Article
Vaivada T, Akseer N, Akseer S, Somaskandan A, Stefopulos M, Bhutta ZA
Am J Clin Nutr 2020 Sep 14;112(Suppl 2):777S-791S. doi: 10.1093/ajcn/nqaa159. PMID: 32860401Free PMC Article
Beal T, Tumilowicz A, Sutrisna A, Izwardy D, Neufeld LM
Matern Child Nutr 2018 Oct;14(4):e12617. Epub 2018 May 17 doi: 10.1111/mcn.12617. PMID: 29770565Free PMC Article

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